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Jan 2019 DOI 10.14302/issn.2641-5518.jcci-18-2552
T KaraCorresponding author
Department of Pathology, Mersin University Medical School, Mersin, Turkey
This report presents a case of collision tumors of low-grade B-cell lymphoma and poorly differentiated adenocarcinoma in the caceum of a 63-year-old woman. Lymphoma was diagnosed incidentally after appendectomy for a clinical presentation of acute appendicitis. Imaging follow-up demonstrated mesente…
Dec 2018 DOI 10.14302/issn.2641-5526.jmid-18-2488
Juan Luis Fernández-MartínezCorresponding author
Background: Triple Negative Breast Cancer (TNBC) is a type of breast cancer with very bad prognosis. Predicting the histological grade (HG) and the lymph nodes metastasis is crucial for developing more suitable treatment strategies. Methods: We present the main clinical and pathological variables to…
Oct 2018 DOI 10.14302/issn.2372-6601.jhor-18-2396
Anwar Tawfik AminCorresponding author
Although surgery is the main treatment for solid tumors, it could enhance the growth and metastasis of minimal residual cancer. In this review article we have discussed the perioperative changes in cancer cells and surrounding environment as well as the alterations in the immune system. Several tria…
Feb 2018 DOI 10.14302/issn.2639-1716.jn-18-1965
Jamie T. CaraccioloCorresponding author
Lipomatous tumors are among the most common primary musculoskeletal neoplasms affecting both pediatric and adult patient populations. Patient age, tumor location, and imaging features all contribute to the differential diagnosis of musculoskeletal tumors. Tumors identified outside of common patient…
Dec 2017 DOI 10.14302/issn.2766-8630.jrnm-17-1770
Emad Y. MoawadCorresponding author
The aims of this study are to investigate the variation in the mechanical behaviour of the primary cancer from cancer relapse, and measuring the therapeutic resistance acquired by cancer relapse. A431-cultured cells were irradiated for 7 months until 85 Gy. Then, a selected single cell was left to g…
Nov 2017 DOI 10.14302/issn.2576-6694.jbbs-17-1744
Frouzandeh MahjoubiCorresponding author
Aim: Colorectal cancer is one of the most commonly diagnosed cancers in the world. Cell adhesion molecules play an important role in the progression of various cancers. It has been shown that the high level expression of some Cell adhesion molecule could be a new diagnostic factor for several cancer…
Sep 2017 DOI 10.14302/issn.2324-7339.jcrhap-17-1694
R Berete CoulibalyCorresponding author
Introduction: Squamous cell carcinomas of the conjunctiva (SCC) are rare neoplasia but have a high rate of increase and a high rate of mortality, especially when they occur in the context of Human Immunodeficiency Virus (HIV) infection. The objective of this study was to establish an epidemiological…
Aug 2017 DOI 10.14302/issn.2572-3030.jcgb-14-383
Adrian MaurerCorresponding author
Meningiomas are the most common intracranial tumor in humans. The heterogeneity of these tumors lends difficulty to the genetic, epigenetic, and molecular changes that occur in meningioma pathogenesis, progression, and recurrence. Current de facto classification schemes are based on histologic evalu…
Jul 2017 DOI 10.14302/issn.2575-1212.jvhc-17-1586
Mayara Caroline ROSOLEMCorresponding author
The mammary tumor is one of the most common cancer in female dogs and, at the present days, there is a big focus on the study of the relation between this kind of tumor in animals and the cells that stay around them, like the inflammatory cells. The objective of this study was to evaluate and show w…
Apr 2017 DOI 10.14302/issn.2372-6601.jhor-17-1463
Sylwia SzablewskaCorresponding author
Melanoma is considered to be a very aggressive cancer due to its rapid growth, early and multiple metastases and limited response to standard treatment. Many researchers have hypothesized that the combination of radiation therapy and immunotherapy in the treatment of melanoma primary tumors and meta…
Jul 2016 DOI 10.14302/issn.2471-7061.jcrc-14-575
José V. RoigCorresponding author
Aim: To analyze the factors involved in and the results of stoma reversal after an emergency Hartmann's operation. Methods: A multicenter retrospective study from the Valencian Society of Surgery of patients who had undergone an emergent Hartmann’s operation from 2004 to 2008. An analysis of the rev…
Jun 2016 DOI 10.14302/issn.2372-6601.jhor-16-1125
Jun-ya KatoCorresponding author
Senescence is a powerful mechanism that prevents the development of tumors in vivo; however, once tumors are formed, most are refractory to senescence in response to oncogenic stress. Therefore, a novel pathway leading to senescence is required. We herein demonstrated that the cell cycle regulator C…
Dec 2015 DOI 10.14302/issn.2574-4496.jtc-15-779
Xiaoqi LinCorresponding author
It is extremely rare that sarcomas metastasize to the thyroid. We report a case of a 49 year old male with malignant peripheral nerve sheath tumor (MPNST) metastatic to the thyroid that was diagnosed by ultrasound guided fine needle aspiration (FNA). The FNA cytology showed numerous loosely cohesive…
Jun 2015 DOI 10.14302/issn.2574-4372.jesr-14-607
Michael E. GeuszCorresponding author
Cancer is influenced by the ability of cells to maintain circadian rhythms in molecular and metabolic processes. Disturbance of the underlying circadian timing mechanism in circadian clock cells leads to a higher frequency and more rapid progression of cancer. Cancer stem cells with properties of em…
May 2015 DOI 10.14302/issn.2471-7061.jcrc-14-574
Rosalyn B. IrbyCorresponding author
Colon cancer has a five-year survival of 64.7%, and about 50,000 people are expected to die from colon cancer this year. Patients with metastatic colorectal cancer have a significantly worse prognosis, a 12.9% five-year survival. This emphasizes the need for strategies to inhibit the growth and meta…
May 2015 DOI 10.14302/issn.2572-3030.jcgb-14-495
Ashraf KhanCorresponding author
Thyroid carcinomas encompass a wide spectrum ranging from differentiated thyroid carcinoma (DTC) to poorly differentiated (PDC) and anaplastic thyroid carcinoma (ATC). DTC of both follicular (FTC) and papillary (PTC) types can progress to PDC and AC. The aim of our study was to evaluate if there is…
Jan 2015 DOI 10.14302/issn.2372-6601.jhor-14-377
W Zaidah ACorresponding author
Background Abnormalities of plasma von Willebrand Factor (vWF) system has been described in solid tumors but more information is required to understand the pathophysiological process in haematological malignancies. Objectives This study was carried out to investigate the changes in vWF-related param…
Nov 2014 DOI 10.14302/issn.2379-8572.joa-14-561
samy ElwanyCorresponding author
Pleomorphic adenomas are uncommon tumors of the nasal cavity. They arise from minor salivary glands, and usually originate from the nasal septum. The tumors are more common in middle-aged females. We present a series of 8 cases of intranasal pleomorphic adenomas. Seven of these tumors originated fro…
Jun 2014 DOI 10.14302/issn.2372-6601.jhor-13-379
Takuma HayashiCorresponding author
Sarcomas are neoplastic malignancies that typically arise in tissues of mesenchymal origin. The identification of novel molecular mechanisms leading to sarcoma formation and the establishment of new therapies has been hampered by several critical factors. Human uterine leiomyosarcoma (Ut-LMS) develo…
May 2014 DOI 10.14302/issn.2572-3030.jcgb-13-369
Ashraf KhanCorresponding author
Insulin receptor substrate (IRS) 1 and 2 are downstream signaling proteins that influence breast pathophysiology. IRS-1 promotes carcinoma cell proliferation; whereas IRS-2 regulates cell motility, invasion, and glycolysis. Our lab has shown that distinct cellular localization of IRS-2 also plays a…